Swine feed supplement



United States Patent'O SWINE FEED SUPPLEMENT Jerome L. Martin, Terre Haute, Ind., assignor to Commercial Solvents Corporation, Terre Haute, Ind., a corporation of Maryland No Drawing. Application January 29, 1958 Serial No. 711,774

14 Claims. ((31. 99-2) bacon from Denmark, while ignoring the fatty bacon generally produced on the Northfl American continent. Danish farmersfeed their pigs large amounts of milk. This high protein feed produces'lean, muscular pigs'having little back fat. American farmers prefer tofeed theirs'wine diets containing large amounts of cheap energy sources such as corn, milo, barley, etc. in spite of the fact that the resulting pig does not bring thehighest market prices due to the fact that hams and bacon containing excessive amounts of fat do not sell well.

I have now discovered that swine fed the abovecided decrease in the amount ofback fat formed during growth, while maintaining essentially thesame degree or feed utilization and rate of growth.

Compounds comingwithin the above-described structural formula include: 2,2-dinitropropane, 2,2-dinitrobutane, 2,2-dinitro-1-propanol, 2,2-dinitro-1-propano1 carbamate, 2,2-dinitro-1,3-propanediol dicarbamate, 3,3-dinitropentane, 3,3-dinitro-1-pentanol, 3,3-dinitro-2-pentan01, etc.

My additives may be fed to swine as part of complete feedsor as part of a supplement for the carbohydrate source. Generally, the supplements contain from'about 36 to about 40% protein, and vitamins, minerals, and other nutritive additives which forms. balanced diet when fed to, swine with a particular carbohydrate source. Generally, swine growers prefer to feed the carbohydrate and the protein feed supplement separtely, as the swine,

through free choice, generally eat sufficient amounts of the protein supplement to obtain a balanced diet. From about 25 to about 2500 grams of my active ingredients are needed per ton of supplement where the carbohydrate source and supplement are. fed separtaely. About 5 to about 500 grams of my active ingredients are needed per ton of complete swine feed. If these amounts of my active ingredients are added to the complete feed and supplement the swine exhibit a reduction in back fat 'of about 5 to about 15% and there is no marked decrease in feed utilization efficiency or. rate of growth.

It is to be understood that not all of mycompounds are active to the same degree and that the active ingrediflavin) lb 0.5 Choline feed supplement (25% choline chloride) lb 2 Propionic'acid fermentationresidues (6 mg./lb. vitamin Bm) lb 2.5 Vitamin D (4 million I.U./lb.) grams 91 Calcium pantothenate do 6 Niacin i do 15 Baciferm-PB-IO (zinc bacitracin, 7 .5 g./lb. and

procainejpenicillin 2.5 g./lb.) lb 2.5 Aureomycinsupplement (l0 g. /lb.) lb 1.25 Terramycin supplement (10 g./lb.) lb 1.25

Calculated analysis: 1

. Protein -1 percent ...'16.1

Fat do a 32 Fiber d 3.7 Calcium do 0.78 Phosphorus I do 0.60 VitaminA I.U./lb 3620 Vitamin D I.U./lb 400 Riboflavin mg./lb.. 1.74 Pantothenic acid mg./lb 6.15 'Niacin m /lb..... 16.17 Choline m2 /lb 500 Vitamin B g./lb 7.5 Lysine percent 0.71 Tryptophan do' 0.16 Methionine do 0.31 Cystine do 0.24

ents of my invention may be utilized individually or as mixtures.

The following example is given to illustrate my invention, but it is not intended that my invention be limited to the procedures, amounts .of active ingredients, or deflavin) lb 0.4- Choline feed supplement (25 choline chlo- W 'ride) lb 1.0

2,924,524 Patented Feb. 9, 1960 EXAMPLE I The eflicacy of my invention can be easily demonstrated by feeding pigs complete feeds containing g./ton of 2,2-dinitro-1,3-propanediol and 2,2-dinitro-1-propano1 and comparing-the depth of back fat with the back fat of'pigs fed the same complete feed containnig no additives, duplicate groups of pigs being fed in each case. Different feed formulas'are fed to the pigs at various times during their growth. Thus, a high protein content feed is fed to the younger pigs while a'high carbohydrate content feed is fed to the pigs during the final stages of growth when the pigs are being fattened for market. When the pigs weigh between 45-75 pounds the following complete feed is fed:

Swine' Fo rmulzz A Ground yellow corn lb 1510 Meat and bone scraps, 50% lb 50 Soybean oil meal, 44% ..lb 350 Dehydrated alfalfa meal, 17% lb 50 Ground ,limstone lb '10 Dicalcium phosphate lb .20 Trace mineral salt lb 12 Riboflavin feed supplement (3.6 g./lb. ribo- Betweeni75-125 pounds the following complete feed was utilized:

' Swine Formula B Ground yellow corn lb 1640 Riboflavin feed supplement (3.6; g./lb. ribo- Propionic acid fermentation residues (6 mg./lb.

vitamin B lb. 1.7 Vitamin D (4 million LU/lb.) grams 69 Calcium pantothenate do 5 Niacin do 12 Bacifern-PB-lO (zinc bacitracin, 7.5 g./lb. and

procaine penicillin 2.5 g./lb.) do 227 Aureomycin supplement 10 g./lb.) do 113 Terramycin supplement (10 g./lb.) .do 113 Calculated analysis:

Protein ..-percent-.. 14.0

Fat do 3.4

Fiber dov 3.5

Calcium do 0.67

Phosphorus do 0.49

Vitamin A I.U./lb.... 3718 Vitamin D I.U./lb 300 Riboflavin mg./lb 1.51

Pantothenic acid mg./lb.. 5.48

Niacin m /lb 15.2

Choline m2 /lb 386 Vitamin B gg./lb

' Lysine p'ercent 0.54

Tryptophan 0.13

Methionine do 0.29

Cystine 0.21

Between 125200 pounds the following complete feed is utilized:

Swine Formula C Ground yellow corn lb.. 1750 Meat and bone scraps, 50% lb 50 Soybean oil meal, 44% lb.. 120 Dehydrated alfalfa meal, 17% lb 50 Ground limestone lb 15 Dicalcium phosphate ..lb 7 Trace mineral salt lb 12 Riboflavin feed supplement (3.6 g./lb. ribo- 40 flavin) 1h 0.4 Choline feed supplement (25% choline chloride) lb 1 Fropionic 'acid fermentation residues (6 mg./lb.

vitamin B lb 1.7 Vitamin D (4 million I.U./lb.) grams 69 Calcium pantothenate do 5 Niacin do 12 Baciferm-PB-IO' ('zinc bacitracin, 7.5 g./lb. and

, procaine penicillin 2.5 g./lb. gramsu 227 Aureomycin'supplement(10 g./lb.) do 113 Terramycin supplement (l0 g./lb.) do 113 Calculated analysis:

Protein percent 12.03 Fat do 3.62 Fiber dn 3.26 55 Calcium o 0.68 Phosphorus do 0.45 Vitamin A I.U./lb 3800 Vitamin D I.U./lb 303 Riboflavin mg./1b 1.47 Pantothenic acid mg./lb 5.31 Niacin mg /lb 15.24 Choline 7 m2 /lb 330 Vitamin B hug/lb-.. 5 Lysine .percent 0A2 Tryptophan do 0.11 Methionine do 0.25 1 Cystine dn 0.18

tissue or in muscle. The measured depth of needle penetration, less skin thickness, -determines the thickness of fatty deposits.

In each instance the additive-containing feeds give a 7-8% decrease in depth of. back fat when the pigs are compared with pigs fed the described complete feeds containing no additives.

Now having described my invention, what I claim is:

1. A swine feed containing as an essential active ingredient a small but eflective amount. to reduce the formation of adipose tissue of a compound having the following structural formula:

where, R is a radical selected from the group consisting of hydrogen, lower alkyl, hydroxy,. lower hydroxy alkyl, carbamyl, and lower carbamyl alkyl.

2. A nutrient feed for swine containing as an essential active ingredient a small but effective amount to reduce the formation of adipose tissue of a compound selected from the group consisting: of compounds having the following structural formula:

N O: R-CHE-(J-CHr-R I l oz where R is a radical selected from the group consisting of' hydrogen, lower alkyl, hydroxy, lower hydroxy alkyl, carbamyl, and. lower carbamyl alkyl; and mixtures thereof.

3. A swine feed comprising from about 0.0005 to 0.06% of a compound having theqfollowing structural formula:

'where R is? a radical selected from the group consisting of hydrogen, lower alkyl, hydroxy, lower hydroxy alkyl, carbamyl, and lower carbamyl' alkyl in a nutrient.

4. A. swine feed supplement comprising from about 0.0025 to 0.30% of a compound having the following structural formula:

NO R--CH:CH:-R

where R is a radical selected from the group consisting N0- R-CHr-l-CHa-R I NO: where. R is a radical selected from the group. consisting of hydrogen, lower alkyl, hydroxy, lower hydroxy alkyl, carbamyl, and lower carbamyl alkyl.

6. A process. for the production of swine having decreased amounts of adipose tissue which comprises feeding' said swine a nutrient feed containing from about 0.0005 to. about'0.06% of. a compound having the following structuralformula:

where R is a radical selected from the group consisting of hydrogen, lower alkyl, hydroxy, lower hydroxy elkyl,

' carbamyl, and lower carbamyl alkyl.

7 A process for the production of swine which comprises feeding said swine corn and a nutrient ration containing from about 0.0025 to about 0.30% of a compound having the following structural formula:

I 0.30% of 2,2-dinitropropane in a nutrient.

9. A swine feed comprising from about 0.0005 to about 0.30% of 2,2-dinitro-1-propanol in a nutrient.

10. A swine feed comprising from about 0.0005 to about 0.30% of 2,2-dinitro-l-propanol discarbamate in a nutrient.

11. A swine feed comprising from about 0.0005 to about 0.30% of 2,2-dini'tro-1,3-propanediol in a nutrient.

12. A swine feed comprising from about 0.005 to about 0.30% of 2,2-dinitro1,3-propanediol dicarbamate in a nutrient.

13. A swine feed comprising from about 0.0005 to about 0.30% of 2,2-dinitrobutane in a nutrient.

14. A swine feed comprising from about 0.0005 to about 0.30% of 2,2-dinitro-1-butanol in a nutrient.

References Cited in the file of this patent Agr. News Letter, Du Pont de Nemours & Co., summer 1957, vol. 25, pp. 3 and 4. 

1. A SWINE FEED CONTAINING AS AN ESSENTIAL ACTIVE INGREDIENT A SMALL BUT EFFECTIVE AMOUNT TO REDUCE THE FORMATION OF ADIPOSE TISSUE OF A COMPOUND HAVING THE FOLLOWING STRUCTURAL FORMULA: 